Alberto Broniscer Selected Research

dipinacoline glutamate

1/2022	Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
1/2021	Phase I study using crenolanib to target PDGFR kinase in children and young adults with newly diagnosed DIPG or recurrent high-grade glioma, including DIPG.
3/2020	Radiation dose response of neurologic symptoms during conformal radiotherapy for diffuse intrinsic pontine glioma.
1/2020	Improving long-term survival in diffuse intrinsic pontine glioma.
1/2020	Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma.
1/2020	Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG.
1/2020	A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study.
1/2019	H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
1/2019	Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas.
1/2019	Evaluation of 11C-Methionine PET and Anatomic MRI Associations in Diffuse Intrinsic Pontine Glioma.

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Alberto Broniscer Research Topics

Disease

42	Neoplasms (Cancer) 01/2022 - 01/2004
37	Glioma (Gliomas) 07/2022 - 01/2004
26	Brain Neoplasms (Brain Tumor) 01/2022 - 07/2007
25	Diffuse Intrinsic Pontine Glioma 01/2022 - 11/2010
9	Medulloblastoma 01/2021 - 10/2006
5	Exanthema (Rash) 01/2020 - 06/2008
5	Glioblastoma (Glioblastoma Multiforme) 08/2017 - 01/2004
4	Hemorrhage 01/2020 - 03/2006
4	Diarrhea 10/2019 - 07/2007
4	Hearing Loss (Hearing Impairment) 04/2015 - 04/2014
4	Central Nervous System Neoplasms 03/2015 - 07/2007
3	Disease Progression 01/2016 - 01/2005
3	Ototoxicity 03/2015 - 08/2008
3	Rhabdoid Tumor (Rhabdoid Tumors) 04/2012 - 03/2005
3	Astrocytoma (Pilocytic Astrocytoma) 06/2009 - 02/2007
2	Brain Stem Neoplasms (Brain Stem Tumor) 01/2020 - 04/2008
2	Neoplasm Metastasis (Metastasis) 01/2020 - 12/2010
2	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 01/2014 - 02/2006
2	Primitive Neuroectodermal Tumors (PNET) 04/2012 - 03/2004
2	Infections 06/2008 - 03/2007
2	Neutropenia 06/2008 - 01/2005
1	Typical Teratoid Rhabdoid Tumor 06/2022
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Craniopharyngioma (Craniopharyngiomas) 11/2020
1	Neurologic Manifestations (Neurological Manifestations) 03/2020
1	Nervous System Diseases (Neurological Disorders) 01/2020
1	Arthralgia (Joint Pain) 12/2019
1	Cytopenia 02/2018
1	Vomiting 02/2018
1	Genetic Predisposition to Disease (Genetic Predisposition) 12/2017
1	Abscess 05/2015
1	2-Hydroxyglutaricaciduria 03/2015
1	Primary Ovarian Insufficiency 01/2015

Drug/Important Bio-Agent (IBA)

26	dipinacoline glutamateIBA 01/2022 - 12/2010
8	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2020 - 03/2007
6	Biological ProductsIBA 01/2021 - 03/2006
6	Cisplatin (Platino)FDA LinkGeneric 04/2015 - 08/2008
5	Histones (Histone)IBA 01/2022 - 01/2012
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2009
5	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 01/2005
4	Phosphotransferases (Kinase)IBA 01/2021 - 01/2009
4	ErbB Receptors (EGF Receptor)IBA 10/2019 - 11/2010
4	vandetanib (ZD6474)IBA 09/2013 - 11/2010
3	Methionine (L-Methionine)FDA Link 07/2022 - 01/2022
3	EnzymesIBA 01/2022 - 01/2009
3	OSI-420IBA 02/2020 - 01/2009
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 10/2010
3	Dasatinib (BMS 354825)FDA Link 01/2018 - 06/2013
3	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 09/2013 - 11/2010
3	Farnesyltranstransferase (Farnesyltransferase)IBA 03/2011 - 07/2007
2	RNA (Ribonucleic Acid)IBA 01/2020 - 10/2010
2	dabrafenibIBA 12/2019 - 12/2019
2	CrizotinibIBA 01/2018 - 06/2014
2	Alkylating AgentsIBA 01/2015 - 03/2005
2	Amifostine (Ethyol)FDA LinkGeneric 06/2014 - 08/2008
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2014 - 11/2010
2	Vincristine (Oncovin)FDA LinkGeneric 08/2012 - 08/2008
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2012 - 08/2008
2	tipifarnib (R115777)IBA 03/2011 - 06/2008
2	Gefitinib (Iressa)FDA Link 03/2011 - 12/2010
1	MLN 8237IBA 06/2022
1	Amino Acids FDA Link 01/2022
1	Methionine AdenosyltransferaseIBA 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Mitogen-Activated Protein KinasesIBA 01/2022
1	tyrosyltyrosine (Tyr-Tyr)IBA 01/2021
1	LigandsIBA 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	crenolanibIBA 01/2021
1	InterferonsIBA 11/2020
1	veliparibIBA 01/2020
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 10/2019
1	Capecitabine (Xeloda)FDA Link 02/2018
1	TabletsIBA 02/2018
1	Alanine Transaminase (SGPT)IBA 02/2018
1	Monophenol Monooxygenase (Tyrosinase)IBA 01/2018
1	Topotecan (Hycamtin)FDA LinkGeneric 01/2016
1	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 05/2015
1	posaconazole FDA Link 05/2015
1	Micafungin (FK463)FDA Link 05/2015
1	alpha-hydroxyglutarateIBA 03/2015
1	Methotrexate (Mexate)FDA LinkGeneric 01/2015

Therapy/Procedure

36	Radiotherapy 01/2021 - 01/2004
22	Therapeutics 01/2021 - 01/2004
14	Drug Therapy (Chemotherapy) 01/2016 - 01/2004
7	Craniospinal Irradiation 09/2015 - 03/2008
3	Aftercare (After-Treatment) 09/2015 - 08/2008
3	Hearing Aids (Hearing Aid) 06/2014 - 08/2008
2	Conformal Radiotherapy 03/2020 - 12/2014
1	Immunotherapy 01/2021
1	Retreatment 01/2020
1	Re-Irradiation 01/2020
1	Duration of Therapy 12/2019
1	Biological Therapy 01/2018
1	Ambulatory Care (Outpatient Care) 01/2016
1	Combined Modality Therapy 01/2016
1	Palliative Care (Palliative Therapy) 01/2016
1	Cytoreduction Surgical Procedures 01/2016
1	Adjuvant Chemotherapy 01/2015